PCR cabinets

Labman BV is official distributor for CleanAir by Baker PCR cabinets and other laboratory cabinets for Belgium.

Logo Cleanair By Baker

Labman BV is official distributor for Erlab PCR cabinets and other filtration technologies for Belgium, Netherlands and Luxembourg.

Logo Erlab
CleanAir by Baker PCR laminar flow cabinet for polymerase chain reaction work.

Laminar flow cabinets or clean benches provide a sterile work environment by HEPA filtered air. The blowers take room air and push it through filters that remove all contaminants. The filtered air creates a positive pressure inside the laminar flow cabinet, preventing contaminants from entering the cabinet. Laminar flow cabinets do not protect the user and environment against hazardous products used inside the clean. If you are handling biohazards, please visit our biosafety cabinet page. If you are handling hazardous chemical, please visit our fume hood page. 

There are 2 different types of laminar flow cabinets: horizontal laminar flow cabinets and vertical laminar flow cabinets.

Horizontal laminar flow cabinets: the HEPA filter is positioned at the back of the hood and the unidirectional air flow goes horizontally towards the work opening.

Vertical laminar flow cabinets: The HEPA filter is positioned in the sealing of the hood and the unidirectional air flow goes vertically towards the work surface.

Frequently asked questions

Answer:
A PCR cabinet is used to protect DNA and RNA samples from airborne contamination during polymerase chain reaction (PCR) preparation. It provides a sterile, particle-free working environment using vertical laminar airflow and HEPA filtration.

Between 2 PCR cycles, UV light can easily be activated to inactivate DNA or RNA copies from the previous cycle. 

PCR cabinets prevent cross-contamination between samples, a critical factor for ensuring accurate and reproducible results. They minimize the risk of false positives or degraded amplification by maintaining ISO Class 5 air quality around the workspace. False positives can be caused by strains left from a previous PCR cycle, airborne micro-organisms or free DNA.

A PCR cabinet protects the sample from contamination but does not protect the user or the environment from biohazards. In contrast, a biosafety cabinet protects both the user and the environment from infectious materials, in addition to protecting the samples. Also typically biological safety cabinets are less optimized for UV decontamination.

A PCR cabinet and a dead air box both aim to protect sensitive samples during PCR preparation, but they operate differently. Both are optimized to apply UV decontamination between PCR cycles. A PCR cabinet uses active vertical laminar airflow combined with HEPA filtration to continuously deliver particle-free, sterile air across the workspace, maintaining ISO Class 5 conditions. In contrast, a dead air box is a passive enclosure without airflow; it simply acts as a physical barrier to reduce exposure to airborne contaminants. While dead air boxes provide basic protection for low-risk applications, PCR cabinets offer superior contamination control, especially critical for high-sensitivity PCR workflows where even minimal contamination can impact results.

UV decontamination uses ultraviolet light (typically UV-C) to break down and deactivate DNA molecules on surfaces inside the cabinet. This reduces the risk of carryover contamination between PCR runs, enhancing reliability and sample integrity.

PCR cabinet by CleanAir by Baker

PCR cabinets by Erlab

Not sure what device suits you best? Get in contact with us for a free consultancy and get the most optimal configuration for your lab needs.

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